裴新梧研究员

博士后
研究员
博士生导师

peixinwu@caas.cn
研究中心

农业生物安全

创新团队

基因安全评价与检测

课 题 组

裴新梧课题组

招生方向

生物化学与分子生物学

学习工作经历

1999年获兰州大学生命科学院博士学位。
1999年至2001年中国农业科学院博士后。
2001年至今在中国农业科学院生物技术研究所。
2007年1月至今中国农业科学院生物技术研究所研究员。

社会兼职:中国植物保护学会生物安全专业委员会委员,海南大学客座教授。

主要研究领域与成果

主要从事转基因作物安全和植物功能基因组学等方面的研究。

先后主持完成了国家863项目、自然科学基金、国家科技重大专项等研究课题。在转基因作物环境安全评价方面,完成了我国玉米、水稻基因飘流的空间分布特征和主产区各县的最大阈值距离研究,为我国转基因玉米、水稻的基因飘流风险管控提供重要技术支持。在植物功能基因研究方面,克隆并鉴定出一批植物抗旱和调控脂肪代谢的相关基因。克隆自沙生植物柠条的抗旱基因已应用于作物分子育种。利用EMS诱变,获得抗苯磺隆类除草剂的胡麻突变体材料,已应用与胡麻主产区。

主编《水稻转基因飘流》,参编《中国植物保护百科全书-生物安全卷》等专著4部。授权国家发明专利5项。获省科技进步二等奖两项。发表SCI研究论文46篇,指导培养研究生26名。

主要发明专利:

  1. 根特异启动子OrRSGp及其应用, 专利号:ZL 201810612767.8,裴新梧,龙艳,黄珂

  2. 绿色组织特异表达基因启动子及其应用,专利号:ZL 201810612890X,裴新梧,龙艳,薛满德,赵志强

  3. 特异DNA 片段com58276及其在调控植物抗逆性中的应用,裴新梧,龙艳,梁凤萍,专利号:ZL201910957559.6

  4. 蛋白质CkWRKY33及其编码基因与应用,龙艳,裴新梧,梁凤萍,专利号: ZL 201911105373.4

  5. 抗磺酰脲类除草剂胡麻的抗性基因及其应用,裴新梧,龙艳,刘彩月 专利号:202210897818.2

发表论文(通讯作者):

  1. Yang X, Niu X, Li L, Wang L, Liu C, Liu J, Yuan Q*, Pei X*. Understanding the molecular mechanism of drought resistance in Shanlan upland rice by transcriptome and phenotype analyses. International Journal of Biological Macromolecules. 2023.21:123387. doi: 10.1016/j.ijbiomac.2023.123387.

  2. Caiyue Liu, Tianbao Zhang, Xinsen Yang, Liu Wang, Yan Long, Agula Hasi, Xinwu Pei*. A LuALS mutation with high sulfonylurea herbicide resistance in Linum usitatissimum L. Int J Mol Sci. 2023.24(3):2820. doi.10.3390/ ijms 24032820.

  3. Yang X, Liu C, Tang Q, Zhang T, Wang L, Zhang J, Pei X*. Identification of LncRNAs and Functional Analysis of ceRNA Related to Fatty Acid Synthesis during Flax Seed Development. Genes. 2023.14.967. doi.org/10.3390/genes 14050967.

  4. Yuanchun Pu , Peilin Wang, Jiangling Xu , Yejun Yang, Ting Zhou, Kai Zheng, Xinwu Pei*, Quanjia Chen, Guoqing Sun. Overexpression of the Caragana korshinskii com58276 Gene Enhances Tolerance to Drought in Cotton (Gossypium hirsutum L.). Plants. 2023.27;12(5):1069. doi: 10.3390/ plants12051069.

  5. Rongju Li, Yinling Huang, Xinsen Yang, Meng Su, Huaiyang Xiong, Yang Dai, Wei Wu, Xinwu Pei* and Qianhua Yuan*. Genetic Diversity and Relationship of Shanlan Upland Rice Were Revealed Based on 214 Upland Rice SSR Markers. Plants. 2023.12.2876. doi.org/10.3390/plants12152876.

  6. Xinsen Yang, Caiyue Liu, Xiaoling Niu, Liu Wang, Laiyi Li, Qianhua Yuan*, Xinwu Pei*. Research on lncRNA related to drought resistance of Shanlan upland rice. BMC Genomics. 2022. Apr 30;23(1):336. doi.org/10.1186/s12864-022-08546-0.

  7. Hu Ning, Hu Jichao,Jiang Xiaodong, Xiao Wei, Yao, Kemin, Li Liang, Li Xinhai Pei Xinwu*. Application of the maximum threshold distances to reduce gene flow frequency in the coexistence between genetically modified (GM) and non-GM maize. Evolutionary Applications. 2022.10.1111/eva.13361.

  8. Xiaoling Niu, Nanxin Zhai, Xinsen Yang, Meng Su, Caiyue Liu, Liu Wang, Pengzheng Qu, Wuge Liu, Qianhua Yuan, Xinwu Pei*. Identification of Drought-Resistant Genes in Shanlan Upland Rice. Agriculture. 2022.10.3390/12020150. doi.org/10.3390/agriculture12020150.

  9. Zhen Li, Hui Chi, Caiyue Liu, Tianbao Zhang, Lida Han, Liang Li, Xinwu Pei* and Yan Long*. 2021. Genome-wide identification and functional characterization of LEA genes during seed development process in linseed flax (Linum usitatissimum L.). BMC plant biology.21(1):193. doi.org/10.1186/s12870-021-02972-0.

  10. Zhen Li, Fengping Liang, Tianbao Zhang, Na Fu, Xinwu Pei* and Yan Long*.  Enhanced tolerance to drought stress resulting from Caragana korshinskii CkWRKY33 in transgenic Arabidopsis thaliana. BMC Genomic Data. 2021. 22(1):11. doi.org/10.1186/s12863-021-00965-4.

  11. Ning Hu, Xiaodong Jiang, Qianhua Yuan, Wuge Liu, Kemin Yao, Yan Long , Xinwu Pei*. Increased pollen source area does not always enhance the risk of pollen dispersal and gene flow in Oryza sativa L. Scientific Reports. 2020.10: 6143. doi.org/10.1038/s41598-020-63119-z.

  12. Huiyun Liu, Ke Wang, Huali Tang, Qiang Gong, Lipu Du, Xinwu Pei*, Xingguo Ye*, CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain thresh ability, Journal of Genetics and Genomics, doi.org/ 10.1016/j.jgg. 2020.08.004.

  13. Tianbao Zhang, Zhen Li, Xiaxia Song, Lida Han, Limin Wang, Jianping Zhang, Yan Long* and Xinwu Pei*. Identification and Characterization of microRNAs in the Developing Seed of Linseed Flax (Linum usitatissimum L.). International Journal of Molecular Sciences. 2020, 21(8): 2708.doi: 10.3390/ijms 21082708.

  14. Huiyun Liu, Ke Wang, Jing Wang, Lipu Du, Xinwu Pei*, Xingguo Ye*. Genetic and agronomic traits stability of marker-free transgenic wheat plants generated from Agrobacterium-mediated cotransformation in T2 and T3 generations. Journal of Integrative Agriculture. 2020,19 (1):23-32.

  15. Yan Long, Fengping Liang, Jingwen Zhang, Mande Xue, Tianbao Zhang, Xinwu Pei. Identification of drought response genes by digital gene expression (DGE) analysis in Caragana korshinskii Kom. Gene. 2020 Jan 30:725:144170. doi: 10.1016/j.gene.2019.144170.

  16. Meidan He, Jiachao Zhang, Linbo Shen, Lixin Xu, Wenjie Luo, Dong Li, Nanxin Zhai, Jianfa Zhao, Yan Long, Xinwu Pei*, Qianhua Yuan*. High-throughput sequencing analysis of microbial community diversity in response to indica and japonica bar-transgenic rice paddy Soils. PLoS ONE. 2019. 14(9): e0222191.

  17. Mande Xue, Yan Long, Zhiqiang Zhao, Gege Huang, Ke Huang, Tianbao Zhang, Qianhua Yuan and Xinwu Pei*. Isolation and Characterization of a Green-Tissue Promoter from Common Wild Rice (Oryza rufipogon Griff.). Int. J. Mol. Sci. 2018.19.doi:10.3390/ijms19072009.

  18. Jiao Wang,Yan Long, Jingwen Zhang, Mande Xue, Gege Huang, Ke Huang, Qianhua Yuan, Xinwu Pei*. Combined analysis and miRNA expression profiles of the flowering related genes in common wild rice (oryza rufipogon Griff.), Genes & Genomics. 2018.1.doi.org/10.1007/s13258-018-0688-y.

  19. Jianping Zhang,Yan Long, Limin Wang, Zhao Dang, Tianbao Zhang, Xiaxia Song, Zhanhai Dang, Xinwu Pei*. Consensus genetic linkage map construction and QTL mapping for plant height-related traits in linseed flax (Linum usitatissimum L.). BMC Plant Biology. 2018. doi.org/10.1186/s12870- 018- 1366-6.

  20. Yanyan Wang, Tianbao Zhang, Xiaxia Song, Jianping Zhang, Zhanhai Dang, Xinwu Pei*, Yan Long. Identification and functional analysis of two alternatively spliced transcripts of ABSCISIC ACID INSENSITIVE3 (ABI3) in linseed flax (Linum usitatissimum L.). PLOS ONE. 2018.doi.org /10.1371/ 0191910.

  21. Jingwen Zhang,Yan Long, Mande Xue, Xingguo Xiao, Xinwu Pei*. Identification of microRNAs in response to drought in common wild rice (Oryza rufipogon Griff.) shoots and roots, PLOS ONE. 2017.10.1371/ 0170330.

  22. Yan Long, Jing Wang, Yanyan Wang, Jinwen Zhang, Jiao Wang, Xinwu Pei*. Comparative analysis of MYB28 homologs and development of a MYB28- specific marker in Brassica napus L. Mol Breeding.2016,36:126. doi:10.1007/s11032-016-0551-2.

  23. Xinjie Tian, Yan Long, Jiao Wang, Jingwen Zhang, Yanyan Wang, Weimin Li, Yufa Peng, Qianhua Yuan, Xinwu Pei*. De novo Transcriptome Assembly of Common Wild Rice (Oryza rufipogon Griff.) and Discovery of Drought- Response Genes in Root Tissue Based on Transcriptomic Data, PLOS ONE, 2015,6. DOI:10.1371 /journal. pone.0131455.

  24. Yan Long, Yanyan WangShanshan WuXinjie TianXinwu Pei*. De Novo De novo assembly of transcriptome sequencing in Caragana korshinskii Kom. and characterization of EST-SSR markers. PLOS ONE.2015,1. doi.org/10.1371 /journal. pone.0115805.

  25. Yan Long, Jingwen Zhang, Xinjie Tian, Shanshan Wu, Qiong Zhang, Jianping, Zhang, Zhanhai Dang and XinWu Pei*. De novo assembly of the desert tree Haloxylon ammodendron (C. A. Mey.) based on RNA-Seq data provides insight into drought response gene discovery and marker identification. BMC Genomics. 2014,15:1111,1471-2164.

  26. ShirongJia, Qianhua Yuan, Xinwu Pei*, Feng Wang, Ning Hu, Kemin Yao, Zhixing Wang. Rice transgene flow: its patterns, model and risk management, Plant Biotechnology Journal. 2014,12.1259-1270Co-first author.

  27. Ning Hu, Jichao Hu, Xiaodong Jiang, ZongzhiLu,YuFa Peng, WanLong chen, Keminyao, MingZhang, ShirongJia, Xinwu Pei*. Establishment and optimization of a regionally applicable maize gene flow model. Trangenic Research. 2014, 5, 795-807.

  28. Zongxiang Chen, Fuli Li, Songnan Yang, Yibo Dong, Qianhua Yuan, Feng Wang, Weimin Li, ShirongJia, XinWu Pei*. Identification and Functional Analysis of Flowering Related microRNAs in Common Wild Rice (Oryza rufipogon Griff.). PLoS One. 2013, 8(12): e82844.

  29. Dong YB, Cheng ZX, Pei XW*, Yuan QH, Wang F, Wu HJ, Peng YF. Variation of the OsGI intron and its phenotypic associations in Oryza rufipogon Griff. and Oryza sativa L. Genetics and Molecular Research. 2013.12 (3): 2652-2669.

  30. Y. Dong, F. Li, X. Pei*, F. Wang, Q. Yuan, H. Wu, S. Jia and Y. Peng. Genome- wide multilocus analysis of intraspecific differentiation in Oryza rufipogon Griff. from China and the influence of introgression from O. sativa L. Genetics and Molecular Research. 2013.12 (4): 6103-6119.

  31. Dong YB, Pei XW*, Yuan QH, Wang F, Wu HJ, Peng YF. Genetic differentiation of Oryz aruffipogon Griff. from Hainan Island and Guangdong, China based on Hd1 and Ehd1 genes. Biochemical Sysematics and Ecology. 2012. 45: 224-236.

  32. Dong YB, Pei XW*, Yuan QH, Wu HJ, Jia SR, Peng YF. Ecological, morphological and genetic diversity in Oryza rufipogon Griff. (Poaceae) from Hainan Island, China. Genetic resources and crop evolution. 2010. 57: 915-926.

  33. 胡凝,姚克敏,袁潜华,贾士荣,何美丹,江晓东,徐立新,胡继超,裴新梧*. 海南南繁区水稻基因飘流的最大阈值距离,中国农业科学,2014, 47(23): 4551-4562.

  34. 《水稻转基因飘流》,裴新梧,袁潜华,胡凝,王丰,姚克敏,贾士荣著,科学出版社,2016.1.